RSSDI Repository, Complications of Diabetes Demonstration
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Addressing selectivity issues of aldose reductase 2 inhibitors for the management of diabetic complications.

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2020 Jul Others M Kumar, S Choudhary, PK Singh… - Future Medicinal …, 2020 - Future Science

Full Author : ['Kumar, Manoj', 'Choudhary, Shalki', 'Singh, Pankaj Kumar', 'Silakari, Om']
Journal Title : Future medicinal chemistry
Chapter : Section8
Journal Year : 2020
Cited by : 14

Aldose Reductase 2 (ALR2), the rate-limiting enzyme of the polyol pathway, plays an important role in detoxification of some toxic aldehydes. Under hyperglycemia, this enzyme overactivates and causes diabetic complications (DC). Therefore, ALR2 inhibition..... Read More

Keywords : ['aldose reductase inhibitor', 'address selectivity issue', 'diabetic complication', 'management']
PubMed Link : https://www.future-science.com/doi/abs/10.4155/fmc-2020-0032
Google Scholar Link : https://scholar.google.com/scholar?cites=17489673463607323809&as_sdt=5,31&sciodt=0,31&hl=en&num=20