RSSDI Repository, Complications of Diabetes Demonstration
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  • Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk.

Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk.

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2016 Jul Others N Vedovato, E Cliff, P Proks, V Poovazhagi… - Diabetologia, 2016 - Springer

Full Author : ['Vedovato, Natascia', 'Cliff, Edward', 'Proks, Peter', 'Poovazhagi, Varadarajan', 'Flanagan, Sarah E', 'Ellard, Sian', 'Hattersley, Andrew T', 'Ashcroft, Frances M']
Journal Title : Diabetologia
Chapter : Section3, Section5
Journal Year : 2016
Cited by : 29

AIMS/HYPOTHESIS: The pancreatic ATP-sensitive potassium (KATP) channel plays a pivotal role in linking beta cell metabolism to insulin secretion. Mutations in KATP channel genes can result in hypo- or hypersecretion of insulin, as in neonatal diabetes mel..... Read More

Keywords : ['atp sensitivity markedly affect diabete risk', 'neonatal diabete cause', 'homozygous mutation demonstrate', 'tiny change']
PubMed Link : https://link.springer.com/article/10.1007/s00125-016-3964-x
Google Scholar Link : https://scholar.google.com/scholar?cites=13220666477112000987&as_sdt=400005&sciodt=0,14&hl=en&num=20