Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial.

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2017 Jul 15 RCTs Fist_Author_Year_PM 5

Full Author : ['Avidan, Michael S', 'Maybrier, Hannah R', 'Abdallah, Arbi Ben', 'Jacobsohn, Eric', 'Vlisides, Phillip E', 'Pryor, Kane O', 'Veselis, Robert A', 'Grocott, Hilary P', 'Emmert, Daniel A', 'Rogers, Emma M', 'Downey, Robert J', 'Yulico, Heidi', 'Noh, Gyu-Jeong', 'Lee, Yonghun H', 'Waszynski, Christine M', 'Arya, Virendra K', 'Pagel, Paul S', 'Hudetz, Judith A', 'Muench, Maxwell R', 'Fritz, Bradley A', 'Waberski, Witold', 'Inouye, Sharon K', 'Mashour, George A']
Journal Title : Lancet (London, England)
Chapter : Section8
Journal Year : 2017

BACKGROUND: Delirium is a common and serious postoperative complication. Subanaesthetic ketamine is often administered intraoperatively for postoperative analgesia, and some evidence suggests that ketamine prevents delirium. The primary purpose of this tr.....

Keywords : ['international multicentre doubleblind randomise clinical trial', 'postoperative delirium', 'old adult', 'major surgery', 'intraoperative ketamine', 'prevention', 'pain']

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Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial.